To "make ___" means that you get paid that much for your job. If you say:

I make fifty thousand.

It means that you get paid 50,000 dollars, euros, yen, or whatever form of money is used in your country.

You can tell what the time period is for this amount using "per ___":

I make fifty thousand dollars per year.

A more casual way of saying the same idea is "make ___ a ___":

She only makes ten bucks an hour.