There's a simpler way to say the example sentence above:

This means that everything needs to be in by Wednesday.

Or just:

Everything needs to be in by Wednesday.

But adding "What that means for you guys..." to the beginning gives this sentence more emphasis. The people in the meeting will pay more attention to it and probably remember it better. Here are some more examples:

What that means for small business owners is that your taxes may actually decrease this year, depending on how much you earn.

Here's an example that's a little different but still formed in the same way. It uses "shows" instead of "means":

What this chart shows is that people with a college degree earn, on average, $900,000 more during their lives than people with only a high school diploma.